MHY553
Catalogue number:
CAY36088-10 mg
Supplier:
Size:
10 mg
Product is available in:
£328.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
6265-56-1
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
243.3
Alternative Names:
4-(2-benzothiazolyl)-1,3-benzenediol, nsc 33005
- Data sheet: View or download
- MSDS: View or download
Product Description:
An agonist of PPARα; activates PPARα in HepG2 cells in a reporter assay at 1 µM but does not activate PPARβ or PPARγ at 10 µM; prevents T0901317-induced triglyceride accumulation in HepG2 cells at 3 µM; scavenges ROS and peroxynitrite in cell-free assays (IC50s = 39.7 and 2.39 µM, respectively); inhibits β-glucuronidase and tyrosinase (IC50s = 8.9 and 0.01 µM for the bovine liver and mushroom enzymes, respectively); reduces age-induced increases in liver weight and triglyceride levels in a rat model of hepatic steatosis at 5 mg/kg
Storage Temperature:
-20°C