FSEN1
Catalogue number:
CAY38025-10 mg
Supplier:
Size:
10 mg
Product is available in:
£260.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
862808-01-3
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
484.4
Alternative Names:
3-(4-bromophenyl)-6-[[4-(4-methoxyphenyl)-1-piperazinyl]methyl]-thiazolo[2,3-c]-1,2,4-triazole, ferroptosis sensitizer 1
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of FSP1 (IC50 = 313 nM); selective for FSP1 over NQO1 (IC50 = >100 µM); induces cell death in GPX4-/- H460 cells (EC50 = 69.36 nM); sensitizes various cancer cells to (1S,3R)-RSL3-induced ferroptosis from 10-1,000 nM; sensitizes H460Cas9 cells to dihydroartemisinin- or FINO2-induced cell death
Storage Temperature:
-20°C