RO9021
Catalogue number:
CAY37543-25 mg
Supplier:
Size:
25 mg
Product is available in:
£406.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1446790-62-0
Purity:
≥90%
Formulation:
A solid
Molecular Weight:
355.4
Alternative Names:
6-[[(1r,2s)-2-aminocyclohexyl]amino]-4-[(5,6-dimethyl-2-pyridinyl)amino]-3-pyridazinecarboxamide, chembl 3237561
- Data sheet: View or download
- MSDS: View or download
Product Description:
A Syk inhibitor (IC50 = 5.6 nM); selective for Syk over a panel of 392 other kinases at 1 µM; inhibits M. tuberculosis PknG (IC50 = 4.4 µM); inhibits the proliferation of, and induces apoptosis in, primary AML cells at 5 µM; prevents RANKL- and M-CSF-induced osteoclastogenesis in isolated mouse BMDMs (IC50 = 145 nM); reduces disease severity in a mouse model of collagen-induced arthritis at 5 or 45 mg/kg
Storage Temperature:
-20°C