UC2288
Catalogue number:
CAY37380-25 mg
Supplier:
Size:
25 mg
Product is available in:
£280.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1394011-91-6
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
481.8
Alternative Names:
n-[4-chloro-3-(trifluoromethyl)phenyl]-n′-[trans-4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]cyclohexyl]-urea
- Data sheet: View or download
- MSDS: View or download
Product Description:
A p21WAF1 inhibitor; reduces the protein levels and mRNA expression of p21WAF1 independently of Raf and p53, respectively, at 10 µM; decreases the proliferation of, and phosphorylation of EGFR and ERK1/2 in, CNE-2 and 5-8F cell lines at 8 µM; reduces tumor growth and induces apoptosis in an HCT116 colorectal cancer mouse xenograft model at 15 mg/kg three times per week in combination with imetelstat
Storage Temperature:
-20°C