MI-2-2
Catalogue number:
HY-108350-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1454920-20-7
Purity:
99.92
Molecular Weight:
415.5
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MI-2-2 is a potent menin-MLL inhibitor. MI-2-2 binds to menin with low nanomolar affinity (Kd=22nM) and very effectively disrupts the bivalent protein-protein interaction between menin and MLL. MI-2-2 has specific and very pronounced activity in MLL leukemia cells, including inhibition of cell proliferation, down-regulation of Hoxa9 expression, and differentiation[1].
Storage Temperature:
-20°C (Powder, sealed storage, away from moisture and light)