This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2067281-51-8
Purity:
99.06
Molecular Formula:
C20H25F3N8O4
Molecular Weight:
498.46
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PF-06843195 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy[1].
Storage Temperature:
-20°C, 3 years; 4°C, 2 years (Powder)