YM-244769
Catalogue number:
HY-136182A-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
838819-70-8
Purity:
98.04
Molecular Weight:
443.47
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
YM-244769 is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor. YM-244769 preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode), with IC50s of 18 nM and 50 nM, respectively. YM-244769 efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. YM-244769 can also increase urine volume and urinary excretion of electrolytes in mice[1][2][3].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)