Ruxolitinib, Phosphate
Catalogue number:
BPS-27059-1
Supplier:
Size:
25 mg _$$_
Product is available in:
CAS Number:
1092939-17-7
Purity:
≥99%
Molecular Weight:
404.3
- Data sheet: View or download
Product Description:
Ruxolitinib, also known as INCB18424, is a potent and selective Janus kinase JAK1 and JAK2 inhibitor, with IC50s of 5.9 nM and 5.7 nM, respectively. It inhibited IL-6 and IL-23 effects at concentrations less than 50 nM. Ruxolitinib was effective in the rat adjuvant arthritis model and multiple murine models of arthritis.
Storage Temperature:
Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored a