CAS Number:
418805-02-4
Purity:
>98% by TLC.
Molecular Weight:
371.3
Product Description:
PYR-41 is a cell permeable, irreversible inhibitor of ubiquitin activating enzyme E1 with little or no activity against E2s or E3s (IC50 < 10 µM). It blocks degradation of p53 and inhibits NF-κappaB-dependent pathways. PYR-41 also increases SUMOylation of proteins.
Storage Temperature:
Store at 4°C. Stable as supplied for up to 2 years when stored dessicated at 4°C. Store solutions at