This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
208255-80-5
- Data sheet: View or download
- MSDS: View or download
Product Description:
DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment.
Storage Temperature:
Powder, -20°C, 3 yrs