This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2803881-11-8
- Data sheet: View or download
- MSDS: View or download
Product Description:
MRT-2359 is a potent, orally active and selective GSPT1 depressant (IC50: >30 nM and <300 nM) that specifically induces apoptosis dependent on protein translation. MRT-2359 exhibits significant and preferred anti-proliferative activity in a variety of cancer cell lines, especially MYC-driven cell lines, such as non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) with high expression of N-Myc or L-Myc. MRT-2359 inhibits the growth of drug-resistant NSCLC and SCLC cells, making it suitable for cancer research.
Storage Temperature:
Powder, -20°C, 3 yrs