Abiraterone Acetate
Catalogue number:
CAY15148-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
£859.00
Estimated delivery Fri 2 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
154229-18-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
391.6
Alternative Names:
(3β)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol, acetate ester, cb-7630
- Data sheet: View or download
- MSDS: View or download
Product Description:
A CYP17A1 inhibitor (IC50s = 17 and 18 nM for inhibition of C17,20-lyase and 17α-hydroxylase activities, respectively); prodrug form of abiraterone; reduces plasma testosterone levels, increases plasma luteinizing hormone levels, and reduces ventral prostate, seminal vesicle, testis, and kidney weight in mice at 0.1 and 0.5 mmol/kg per day; reduces SARS-CoV-2 viral load in the culture supernatant of infected Vero E6 cells (EC90 = 8.4 µM) and is active in a plaque reduction assay (EC50 = 1.94 µM)
Storage Temperature:
-20°C