£142.00
Estimated delivery Fri 2 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
154229-21-7
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
347.5
Alternative Names:
17-(3-pyridinyl)-androsta-4,16-dien-3-one, cb 7627, d4a
- Data sheet: View or download
- MSDS: View or download
Product Description:
An active metabolite of abiraterone; androgen receptor antagonist (IC50 = 5.3 nM); reduces expression of androgen receptor target genes in LNCaP, LAPC4, and C4-2 cell lines; inhibits CYP17A1 at 1 nM; blocks SRD5A conversion of Δ4-androstenedione to 5α-androstanedione in LAPC4 cells at 10 µM; delays tumor progression in a VCaP mouse xenograft model; increases progression-free survival in a C4-2 mouse xenograft model
Storage Temperature:
-20°C
