SGI-1776
Catalogue number:
CAY16423-5 mg
Supplier:
Size:
5 mg
Product is available in:
£181.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1025065-69-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
405.4
Alternative Names:
n-[(1-methyl-4-piperidinyl)methyl]-3-[3-(trifluoromethoxy)phenyl]-imidazo[1,2-b]pyridazin-6-amine, pim-kinase inhibitor ix
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of all three human Pim kinases (IC50s = 7, 363, and 69 nM for Pim-1, Pim-2, and Pim-3, respectively); induces apoptosis in lymphocytes from patients with CML or ALL; enhances the activity of sunitinib against renal cell carcinoma and resensitizes chemoresistant cancer cells to taxanes
Storage Temperature:
-20°C