RVX-208
Catalogue number:
CAY16424-5 mg
Supplier:
Size:
5 mg
Product is available in:
£142.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1044870-39-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
370.4
Alternative Names:
2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3h)-quinazolinone
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective antagonist of BET bromodomains, binding with 10-100-fold higher affinity for BD2 (IC50 = 0.04-0.28 µM) over BD1 (IC50 = 1.8-3.1 µM), which causes selective release of BET proteins from chromatin; increases the expression of ApoA1 and reduces atherosclerosis in hyperlipidemic ApoE-deficient mice
Storage Temperature:
-20°C
