HA-1077 (hydrochloride)
Catalogue number:
CAY10010559-10 mg
Supplier:
Size:
10 mg
Product is available in:
£58.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
203911-27-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
364.3
Alternative Names:
hexahydro-1-(5-isoquinolinylsulfonyl)-1h-1,4-diazepine, dihydrochloride, fasudil
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of ROCK2, PRK-2, MSK1, and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively; has been shown to reduce blood vessel constriction, decreases pulmonary arterial pressure, inhibit tumor angiogenesis, and improve insulin signaling in a diabetic rat model; drug forms are marketed for the treatment of pulmonary arterial hypertension and stable angina
Storage Temperature:
-20°C