£117.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2514-30-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
241.3
Alternative Names:
2-(4-methylphenyl)-1,2-benzisothiazol-3(2h)-one, 2-p-tolyl-1,2-benzisothiazolin-3-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
A reversible, cell-permeable inhibitor of JARID1 family demethylases (IC50s = 6, 3, 4.9, and 28 µM for JARID1A, JARID1B, JARID1C, and JARID1D, respectively); increases trimethylation of H3K4 in HeLa cells and blocks the proliferation of tumor cells expressing high levels of JARID1B
Storage Temperature:
-20°C