SB-525334
Catalogue number:
CAY16281-10 mg
Supplier:
Size:
10 mg
Product is available in:
£168.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
356559-20-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
343.4
Alternative Names:
6-[2-(1,1-dimethylethyl)-5-(6-methyl-2-pyridinyl)-1h-imidazol-4-yl]-quinoxaline, tgf-β ri kinase inhibitor viii
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of the TGF-β receptor 1 (TGF-β R1, ALK5) kinase (IC50 = 14.36 nM); blocks TGF-β1-induced phosphorylation and nuclear translocation of SMAD2/3 as well as TGF-β1-directed gene expression; effective in vivo, preventing the development of fibrosis in animals
Storage Temperature:
-20°C
