Kobe 0065
Catalogue number:
CAY16261-10 mg
Supplier:
Size:
10 mg
Product is available in:
£209.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
436133-68-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
449.8
Alternative Names:
n-(3-chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An orally active Ras inhibitor with selectivity for H-Ras (Ki = 46 µM); inhibits both anchorage-dependent and -independent growth and induces apoptosis of H-RasG12V-transformed NIH 3T3 cells (IC50 = ~1.5 µM); exhibits antitumor activity in mice bearing a xenograft of human colon cancer SW480 cells expressing K-RasG12V at an oral dose of 80 mg/kg
Storage Temperature:
-20°C
