GNF-5
Catalogue number:
CAY16254-10 mg
Supplier:
Size:
10 mg
Product is available in:
£85.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
778277-15-9
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
418.4
Alternative Names:
n-(2-hydroxyethyl)-3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]-benzamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An allosteric inhibitor of Bcr-Abl (IC50 = 0.121 µM); inhibits the Bcr-Abl mutants Bcr-AblG250E, Bcr-AblE255V, and Bcr-AblM351T (IC50s = 4.52, 0.38, and 0.93 µM, respectively); reduces viral titers in IBV-infected Vero cells at 10 µM; increases survival in a recalcitrant mutant Bcr-AblT315I mouse bone marrow transplantation model at 75 mg/kg
Storage Temperature:
-20°C
