CO-1686
Catalogue number:
CAY16244-1 mg
Supplier:
Size:
1 mg
Product is available in:
£89.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1374640-70-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
555.6
Alternative Names:
n-[3-[[2-[[4-(4-acetyl-1-piperazinyl)-2-methoxyphenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]phenyl]-2-propenamide, avl-301
- Data sheet: View or download
- MSDS: View or download
Product Description:
An irreversible inhibitor of mutant forms of EGFR including T790M (Ki = 21.5 nM) with minimal activity at the wild-type EGFR (Ki = 303.3 nM); inhibits the proliferation of NSCLC cells expressing mutant EGFR (GI50s = 7-32 nM) and demonstrates anti-tumor activity in NSCLC EGFR mutant xenograft and transgenic models
Storage Temperature:
-20°C
