(E/Z)-4-hydroxy Tamoxifen
Catalogue number:
CAY17308-25 mg
Supplier:
Size:
25 mg
Product is available in:
£170.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
68392-35-8
Purity:
≥98% (mixture of isomers)
Formulation:
A crystalline solid
Molecular Weight:
387.5
Alternative Names:
4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol, 4-oht, afimoxifene
- Data sheet: View or download
- MSDS: View or download
Product Description:
An active metabolite of tamoxifen; formed from tamoxifen by CYP2D6; cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively); stimulates LC3 lipidation and the formation of autophagic vesicles in MCF-7 cells in a superoxide-dependent manner
Storage Temperature:
-20°C