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HSP-990

Catalogue number:
CAY19149-25 mg
Supplier:
Size:
25 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£743.00 Estimated delivery Fri 9 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

934343-74-5

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

379.4

Alternative Names:

(7r)-2-amino-7-[4-fluoro-2-(6-methoxy-2-pyridinyl)phenyl]-7,8-dihydro-4-methyl-pyrido[4,3-d]pyrimidin-5(6h)-one, ​nvp-hsp990

Product Description:

An Hsp90 inhibitor (IC50s = 0.6, 0.8, and 8.5 nM for Hsp90α, Hsp90β, and GRP94, respectively); dissociates the Hsp90-p23 complex, depleting the client protein c-Met and inducing Hsp70 in c-Met amplified GTL-16 gastric tumor cells; inhibits proliferation of various human tumor cell lines in vitro and in a GTL-16 xenograft model

Storage Temperature:

-20°C

CAY19149-25 mg: HSP-990
CAY19149-25 mg: HSP-990
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