£261.00
Estimated delivery Fri 9 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1168091-68-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
456.2
Alternative Names:
5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)-imidazo[1,5-a]pyridine-6-carboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent, ATP-uncompetitive inhibitor of MEK1 (Ki = 0.13 nM in the presence of ATP); inhibits the proliferation of A375 BRAF(V600E) and HCT116 KRAS(G13D)-mutant cancer cell lines (EC50 = 7 and 42 nM, respectively); upregulates pro-apoptotic BIM
Storage Temperature:
-20°C
