£278.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
859212-16-1
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
576.6
Alternative Names:
n-[3-([4,5'-bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3s)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)-benzamide, inno-406, ns-187
- Data sheet: View or download
- MSDS: View or download
Product Description:
A Bcr-Abl kinase inhibitor (IC50 = 5.8 nM) that is 25- to 55-fold more potent than imatinib in vitro and ≥10-fold more potent in vivo; inhibits 12 out of the 13 most frequent imatinib-resistant Bcr-Abl point mutations, but not the T315I mutation; also targets the Src family kinase Lyn (IC50 = 19 nM)
Storage Temperature:
-20°C
