HM61713
Catalogue number:
CAY19481-5 mg
Supplier:
Size:
5 mg
Product is available in:
£181.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1353550-13-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
486.6
Alternative Names:
n-[3-[[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-4-yl]oxy]phenyl]-2-propenamide, bi-1482694, olmutinib
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of mutant EGFR (IC50 = 0.01 µM for EGFRT790M/L858R); selective for EGFRT790M/L858R over PI3Kα (IC50 = >10 µM); cytotoxic to A549, H1975, H460, and MCF-7 cells (IC50s = 4.29, 0.52, 5.29, and 26.9 µM, respectively); reduces tumor growth in an ETS1-overexpressing doxorubicin-resistant K562 leukemia mouse xenograft model at 30 mg/kg in combination with doxorubicin
Storage Temperature:
-20°C
