£269.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1418308-27-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
390.5
Alternative Names:
6-cyano-n-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1h-indole-4-carboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective EZH2 inhibitor that has activity against both wild-type and Y641F mutant EZH2 (IC50s = 15 and 13 nM, respectively); blocks cellular H3K27 methylation and activates PRC2-specific gene expression; decreases proliferation, cell cycle arrest, and apoptosis in diffused large B cell lymphoma cells carrying Y641 mutations
Storage Temperature:
-20°C
