HSP-990
Catalogue number:
CAY19149-1 mg
Supplier:
Size:
1 mg
Product is available in:
£48.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
934343-74-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
379.4
Alternative Names:
(7r)-2-amino-7-[4-fluoro-2-(6-methoxy-2-pyridinyl)phenyl]-7,8-dihydro-4-methyl-pyrido[4,3-d]pyrimidin-5(6h)-one, nvp-hsp990
- Data sheet: View or download
- MSDS: View or download
Product Description:
An Hsp90 inhibitor (IC50s = 0.6, 0.8, and 8.5 nM for Hsp90α, Hsp90β, and GRP94, respectively); dissociates the Hsp90-p23 complex, depleting the client protein c-Met and inducing Hsp70 in c-Met amplified GTL-16 gastric tumor cells; inhibits proliferation of various human tumor cell lines in vitro and in a GTL-16 xenograft model
Storage Temperature:
-20°C
