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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1589527-65-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
518.5
Alternative Names:
n-[4-[8-amino-3-(1,1-dimethylethyl)imidazo[1,5-a]pyrazin-1-yl]-1-naphthalenyl]-n'-[3-(trifluoromethyl)phenyl]-urea, ire1 inhibitor iv, ire1α kinase inhibiting rnase attenuator 6
- Data sheet: View or download
- MSDS: View or download
Product Description:
An ATP-competitive, allosteric inhibitor of IRE1α RNase kinase activity (IC50 = 0.6 µM); prevents IRE1α oligomerization and promotes cell survival under ER stress in rat models of retinal degeneration and diabetes
Storage Temperature:
-20°C