R-568
Catalogue number:
CAY17415-50 mg
Supplier:
Size:
50 mg
Product is available in:
£913.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
177172-49-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
340.3
Alternative Names:
2-chloro-n-[(1r)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine, monohydrochloride, krn 568, nps r-568, tecalcet
- Data sheet: View or download
- MSDS: View or download
Product Description:
A calcimimetic and positive allosteric modulator of CaSR; potentiates extracellular calcium-induced increases in intracellular calcium release and inhibits the secretion of PTH (IC50 = 27 nM) in bovine parathyroid cells; decreases PTH and plasma calcium levels in rats (ED50s = 1.1 and 10.4 mg/kg, respectively); suppresses parathyroid cell proliferation in a rat model of chronic renal insufficiency at 15 mg/kg
Storage Temperature:
-20°C
