ML-314
Catalogue number:
CAY19550-5 mg
Supplier:
Size:
5 mg
Product is available in:
£223.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1448895-09-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
420.5
Alternative Names:
2-cyclopropyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)-1-piperazinyl]-quinazoline
- Data sheet: View or download
- MSDS: View or download
Product Description:
An NTS1 agonist; selective for NTS1 over NTS2 in a cell-based assay of receptor/β-arrestin complex formation (EC50s = 2 and >80 µM, respectively); inactive in an NTS1 calcium flux assay (EC50 = >80 µM); a positive allosteric modulator that increases binding of radiolabaled neurotensin to NTS1 in a concentration-dependent manner; reduces locomotion in dopamine transporter knockout mice and methamphetamine-exposed mice at 20 and 10-30 mg/kg, respectively; reduces methamphetamine self-administration in rats at 30 mg/kg
Storage Temperature:
-20°C
