A-804598
Catalogue number:
CAY20060-5 mg
Supplier:
Size:
5 mg
Product is available in:
£121.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1125758-85-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
315.4
Alternative Names:
n-cyano-n''-[(1s)-1-phenylethyl]-n'-5-quinolinyl-guanidine
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent and selective competitive antagonist of the P2X7 receptor (IC50s = 9.9 and 10.9 nM in 132N1 cells transfected with the rat or mouse receptor, respectively), inhibits IL-1β release in LPS and IFN-γ-stimulated THP-1 cells (IC50 = 8.5 nM); selective over other P2X and P2Y receptors at concentrations up to 100 µM; prevents footshock-induced increases in IL-1β mRNA in the rat hypothalamus
Storage Temperature:
-20°C
