Epacadostat
Catalogue number:
CAY19875-1 mg
Supplier:
Size:
1 mg
Product is available in:
£42.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1204669-58-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
438.2
Alternative Names:
[c(z)]-4-[[2-[(aminosulfonyl)amino]ethyl]amino]-n-(3-bromo-4-fluorophenyl)-n'-hydroxy-1,2,5-oxadiazole-3-carboximidamide, incb024360
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective IDO1 inhibitor (IC50 = 7.1 nM in HeLa cells); promotes T and natural killer-cell growth, increases IFN-γ production, and reduces conversion to Treg-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells; inhibits tumor growth in tumor-bearing mice in a lymphocyte-dependent manner
Storage Temperature:
-20°C