TPI-1
Catalogue number:
CAY22480-25 mg
Supplier:
Size:
25 mg
Product is available in:
£743.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
79756-69-7
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
253.1
Alternative Names:
2-(2,5-dichlorophenyl)-2,5-cyclohexadiene-1,4-dione, tyrosine phosphatase inhibitor 1
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of protein tyrosine phosphatases; increases phosphorylated substrates of the phosphatase SHP-1 in Jurkat T cells; selective for SHP-1 over SHP-2, having low activity at the SHP-2 substrate pERK1/2; increases pLck-pY394 levels by ~3.3-fold and increases the number of IFN-γ+ spleen cells in mouse spleen ex vivo (~3 mg/kg); inhibits tumor growth in a B16 melanoma mouse xenograft model (3 mg/kg per day, oral)
Storage Temperature:
-20°C
