1,5-Dicaffeoylquinic Acid
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19870-46-3
≥98%
A crystalline solid
516.5
(1s,3r,4r,5r)-1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-cyclohexanecarboxylic acid, 1,3-dicaffeoylquinic acid, 1,5-dcqa
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- MSDS: View or download
An HIV-1 integrase inhibitor and free radical scavenger; inhibits HIV-1 integrase 3' end processing, end joining, and disintegration (IC50s = 0.35, 0.56, and 0.84 µg/ml, respectively); inhibits HIV-1 replication in MT-2 cells (ED50 = 2 µg/ml); dose-dependently reduces the level of free radicals released by FMLP stimulation of PMN cells at 0.25-1 µM; dose-dependently increases cell survival and GSH levels and decreases ROS and LDH release when rat cerebral astrocytes in an oxygen-glucose deprivation/reperfusion assay using rat cerebral astrocytes at 5-100 µM
-20°C
