£74.00
Estimated delivery Fri 2 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2438-72-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
223.3
Alternative Names:
4-butoxy-n-hydroxy-benzeneacetamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An NSAID and a class IIb HDAC inhibitor; inhibits IFN-α production in PBMCs (EC50 = 8.9 µM); induces hyperacetylation of tubulin (IC50 = 2.9 µM); inhibits LTA4 hydrolase and aminopeptidase activity (IC50s = 15.86 and 11.59 µM, respectively); inhibits 5-LO (IC50 = 27 µM); inhibits the production of LTB4 in neutrophils (IC50 = 12.91 µM) and reduces fMLP-induced neutrophil migration at 50 and 100 µM; reduces neutrophil levels, as well as TNF-α and IL-1β protein levels, in BALF in a mouse model of LPS-induced acute lung injury at 100 mg/kg
Storage Temperature:
4°C