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Bufexamac

Catalogue number:
CAY26068-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£74.00 Estimated delivery Fri 2 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2438-72-4

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

223.3

Alternative Names:

4-butoxy-n-hydroxy-benzeneacetamide

Product Description:

An NSAID and a class IIb HDAC inhibitor; inhibits IFN-α production in PBMCs (EC50 = 8.9 µM); induces hyperacetylation of tubulin (IC50 = 2.9 µM); inhibits LTA4 hydrolase and aminopeptidase activity (IC50s = 15.86 and 11.59 µM, respectively); inhibits 5-LO (IC50 = 27 µM); inhibits the production of LTB4 in neutrophils (IC50 = 12.91 µM) and reduces fMLP-induced neutrophil migration at 50 and 100 µM; reduces neutrophil levels, as well as TNF-α and IL-1β protein levels, in BALF in a mouse model of LPS-induced acute lung injury at 100 mg/kg

Storage Temperature:

4°C

CAY26068-50 mg: Bufexamac
CAY26068-50 mg: Bufexamac
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