JQEZ5
Catalogue number:
CAY27457-10 mg
Supplier:
Size:
10 mg
Product is available in:
£253.00
Estimated delivery Tue 6 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1913252-04-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
542.7
Alternative Names:
n-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1h-pyrazolo[3,4-b]pyridine-4-carboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An EZH2 inhibitor (IC50 = 11.1 nM); colony formation of primary human CD34+ CML stem/progenitor cells at 0.5-5 µM; reduces global levels of H3K27me3 in K562 cells; induces regression of tumors in an EZH2-driven transgenic mouse model of lung adenocarcinoma at 75 mg/kg per day
Storage Temperature:
-20°C
