MOZ-IN-3
Catalogue number:
CAY27402-5 mg
Supplier:
Size:
5 mg
Product is available in:
£231.00
Estimated delivery Tue 6 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2055397-18-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
384.4
Alternative Names:
4-fluoro-5-methyl-[1,1'-biphenyl]-3-carboxylic acid, 2-(phenylsulfonyl)hydrazide, wm-8014
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of KAT6A and KAT6B (IC50s = 8 and 28 nM, respectively); selective for KAT6A and KAT6B over KAT5 and KAT7 (IC50s = 224 and 342 nM, respectively); induces cell cycle arrest in and inhibits proliferation of mouse embryonic fibroblasts (IC50 = 2.4 µM) and inhibits proliferation of EMRK1184 lymphoma cells (IC50 = 2.3 µM); induces genetic and morphological changes associated with cellular senescence; decreases global levels of H3K14Ac by 49% and reduces H3K9Ac levels at the transcription start sites of Ezh2, Melk, and E2f2
Storage Temperature:
-20°C
