Rubimaillin
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55481-88-4
≥98%
A crystalline solid
284.3
6-hydroxy-2,2-dimethyl-2h-naphtho[1,2-b]pyran-5-carboxylic acid, methyl ester, mollugin
- Data sheet: View or download
- MSDS: View or download
A naphthohydroquinone with diverse biological activities; inhibits the growth of E. coli and S. aureus in a disc assay at 100 µg per disc; scavenges DPPH free radicals in a cell-free assay (IC50 = 0.7 µM); inhibits ACAT1 and ACAT2 (IC50s = 80 and 22 µM, respectively) and cholesterol ester synthesis (IC50 = 18 µM) in murine macrophages; increases BMP2-induced osteoblastic differentiation of C2C12 mesenchymal progenitor cells; enhances skeletal development in zebrafish larvae; inhibits TNF-α-induced NF-κB reporter gene expression and nuclear translocation of p65 and potentiates TNF-α-induced apoptosis in HeLa cells; reduces tumor growth in a HeLa mouse xenograft model at 25 and 75 mg/kg
-20°C
