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Lenalidomide-C4-NH2 (hydrochloride)

Catalogue number:
HY-115446A-100mg
Supplier:
Size:
100 mg _$$_
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2435715-90-3

Purity:

98.85

Molecular Formula:

C17H22ClN3O3

Molecular Weight:

351.83

Alternative Names:

Cereblon ligand 1 (hydrochloride); E3 ligase Ligand-Linker Conjugates 32 (hydrochloride)

Product Description:

Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC50s of 0.98 nM and 13.7 nM in inhibition of RS4;11 and MOLM-13 acute leukemia cell lines growth, respectively[1].

Storage Temperature:

4°C (Powder, sealed storage, away from moisture)

Lenalidomide-C4-NH2 (hydrochloride)
Lenalidomide-C4-NH2 (hydrochloride)
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