Lenalidomide-C4-NH2 (hydrochloride)
Catalogue number:
HY-115446A-100mg
Supplier:
Size:
100 mg _$$_
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2435715-90-3
Purity:
98.85
Molecular Formula:
C17H22ClN3O3
Molecular Weight:
351.83
Alternative Names:
Cereblon ligand 1 (hydrochloride); E3 ligase Ligand-Linker Conjugates 32 (hydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC50s of 0.98 nM and 13.7 nM in inhibition of RS4;11 and MOLM-13 acute leukemia cell lines growth, respectively[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)