This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
606-58-6
Purity:
99.9
Molecular Formula:
C12H13N5O4
Molecular Weight:
291.26
Alternative Names:
Vengicide
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of 80 nM with affecting IRE1α auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC50 value of 79 nM[1][2][3].
Storage Temperature:
-20°C, 3 years (Powder)
