Valemetostat
Catalogue number:
CAY31674-5 mg
Supplier:
Size:
5 mg
Product is available in:
£344.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1809336-39-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
488
Alternative Names:
(2r)-7-chloro-n-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-2-[trans-4-(dimethylamino)cyclohexyl]-2,4-dimethyl-1,3-benzodioxole-5-carboxamide, (r)-or-s2, ds-3201b
- Data sheet: View or download
- MSDS: View or download
Product Description:
A dual EZH1 and EZH2 inhibitor; inhibits PRC2 containing EZH1 or EZH2 as the catalytic subunit in cell-free assays (IC50s = 8.4 and 2.5 nM, respectively); inhibits trimethylation of histone H3 lysine 27 in HCT116 cells (IC50 = 0.44 nM); inhibits the growth of Karpas-422 DLBCL cells (GI50 = 4.8 nM)
Storage Temperature:
-20°C