www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Icotinib

Catalogue number:
CAY30093-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£181.00 Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

610798-31-7

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

391.4

Alternative Names:

n-(3-ethynylphenyl)-7,8,10,11,13,14-hexahydro-[1,4,7,10]tetraoxacyclododecino[2,3-g]quinazolin-4-amine, bpi 2009h

Product Description:

An EGFR inhibitor (IC50 = 2 nM); selective for EGFR over Abl, Abl2, and c-Src tyrosine kinases at 1,000 nM; inhibits EGFR-mediated tyrosine phosphorylation in A431 cells (IC50 = 45 nM); inhibits the growth of PC-9 and HCC827 NSCLC cells (IC50s = 50 = 8,800 nM), which do not; inhibits migration of HCC827 cells at 100 nM and increases apoptosis by 43.7% at 10 nM; reduces tumor growth in a variety of mouse xenograft models at 50-120 mg/kg per day

Storage Temperature:

-20°C

Details Cat number & supplier Size Price
Myristoyl Glycine CAY30107-5 mg · Cayman Chemical
CAY30107-5 mg
Cayman Chemical
5 mg £150.00
5 mg
view
IOWH-032 CAY30273-5 mg · Cayman Chemical
CAY30273-5 mg
Cayman Chemical
5 mg £74.00
5 mg
view
CAY10746 CAY29814-5 mg · Cayman Chemical
CAY29814-5 mg
Cayman Chemical
5 mg £887.00
5 mg
view
VCP171 CAY30309-5 mg · Cayman Chemical
CAY30309-5 mg
Cayman Chemical
5 mg £181.00
5 mg
view
Oxfendazole CAY29742-5 mg · Cayman Chemical
CAY29742-5 mg
Cayman Chemical
5 mg £81.00
5 mg
view
Vapendavir CAY30546-5 mg · Cayman Chemical
CAY30546-5 mg
Cayman Chemical
5 mg £261.00
5 mg
view
Lersivirine CAY29497-5 mg · Cayman Chemical
CAY29497-5 mg
Cayman Chemical
5 mg £138.00
5 mg
view
CAY10763 CAY30593-5 mg · Cayman Chemical
CAY30593-5 mg
Cayman Chemical
5 mg £769.00
5 mg
view
Solasodine CAY28112-5 mg · Cayman Chemical
CAY28112-5 mg
Cayman Chemical
5 mg £95.00
5 mg
view
CNX-2006 CAY30610-5 mg · Cayman Chemical
CAY30610-5 mg
Cayman Chemical
5 mg £220.00
5 mg
view