BKT 140
Catalogue number:
CAY30689-10 mg
Supplier:
Size:
10 mg
Product is available in:
£1025.00
Estimated delivery Tue 6 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
664334-36-5
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
2159.5
Alternative Names:
n2-(4-fluorobenzoyl)-l-arginyl-l-arginyl-3-(2-naphthalenyl)-l-alanyl-l-cysteinyl-l-tyrosyl-n5-(aminocarbonyl)-l-ornithyl-l-lysyl-d-lysyl-l-prolyl-l-tyrosyl-l-arginyl-n5-(aminocarbonyl)-l-ornithyl-l-cysteinyl-l-argininamide, cyclic (4→13)-disulfide, 4f-ben
- Data sheet: View or download
- MSDS: View or download
Product Description:
A CXCR4 antagonist (IC50 = 0.91 nM); inhibits HIV-1-induced cytopathogenicity in MT-4 cells (EC50 = 4 nM); reduces CXCL12-induced migration of SUP-T1 leukemia and MDA-MB-231 at 100 nM; induces apoptosis in NB4 leukemia and RPMI-8226 multiple myeloma cancer cells at 8 and 40 µM; reduces pulmonary metastasis in an MDA-MB-231 mouse xenograft model; reduces the incidence of arthritis in a mouse model of collagen-induced arthritis
Storage Temperature:
-20°C