Cipargamin
Catalogue number:
CAY30678-10 mg
Supplier:
Size:
10 mg
Product is available in:
£833.00
Estimated delivery Tue 6 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1193314-23-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
390.2
Alternative Names:
(1′r,3′s)-5,7′-dichloro-6′-fluoro-2′,3′,4′,9′-tetrahydro-3′-methyl-spiro[3h-indole-3,1′-[1h]pyrido[3,4-b]indol]-2(1h)-one, kae609, nitd609
- Data sheet: View or download
- MSDS: View or download
Product Description:
An antimalarial agent; inhibits the Na+-ATPase activity of wild-type or mutant PfATP4 (IC50s = 12.3-13.9 and 21.1-32.5 nM, respectively, in P. falciparum membranes); active against the P. falciparum chloroquine-sensitive strain NF54 and chloroquine-resistant strain K1 (IC50s = 0.5 and 0.6 nM, respectively); reduces parasitemia and increases survival in a mouse model of P. berghei infection at 10, 30, and 100 mg/kg
Storage Temperature:
-20°C