IOWH-032
Catalogue number:
CAY30273-10 mg
Supplier:
Size:
10 mg
Product is available in:
£130.00
Estimated delivery Tue 6 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1191252-49-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
545.2
Alternative Names:
3-(3,5-dibromo-4-hydroxyphenyl)-n-[(4-phenoxyphenyl)methyl]-1,2,4-oxadiazole-5-carboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A modulator of CFTR; inhibits CFTR in T84 human colon cells (IC50 = 8.51 µM); has rapid inhibitory and slow potentiating effects on human CFTR with apparent Kd values of 6.1 and 0.64 nM, respectively; potentiates currents through ΔF508-CFTR expressed in X. laevis oocytes at 20 nM; inhibits mouse CFTR with an apparent Kd value of 42.9 µM
Storage Temperature:
-20°C