£260.00
Estimated delivery Fri 2 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
51987-99-6
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
206.2
Alternative Names:
n-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An AQP4 inhibitor (IC50 = 3.1 µM in X. laevis oocytes transfected with AQP4); reduces brain edema and cortical infarction size in a mouse model of MCAO-induced transient focal cerebral ischemia at 200 mg/kg; reduces BALF IL-1α, IL-1β, IL-6, TNF-α, IL-23, and IL-17A levels and neutrophil infiltration, as well as increases survival, in a mouse model of LPS-induced acute lung injury at 200 mg/kg every 6 hours
Storage Temperature:
-20°C