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RHPS4 (methyl sulfate)

Catalogue number:
CAY28543-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£73.00 Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

390362-78-4

Purity:

≥98%

Formulation:

A solid

Molecular Weight:

458.5

Alternative Names:

3,11-difluorohydro-6,8,13-trimethyl-quino[4,3,2-kl]acridinium, methyl sulfate

Product Description:

A telomerase inhibitor (IC50 = 0.33 µM); a ligand for the G-quadruplex; induces telomeric DNA damage in BJ fibroblasts expressing human telomerase at 1 µM; inhibits cell growth in the NCI-60 panel of cancer cell lines (mean GI50 = 13.18 µM), as well as induces cell cycle arrest at the S-G2/M and apoptosis in M14 melanoma cells from 0.5-10 µM; reduces tumor growth in several mouse xenograft models at 10 mg/kg

Storage Temperature:

-20°C

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