YIL 781 (hydrochloride)
Catalogue number:
CAY29217-5 mg
Supplier:
Size:
5 mg
Product is available in:
£181.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1640226-17-0
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
446
Alternative Names:
6-(4-fluorophenoxy)-2-methyl-3-[[(3s)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3h)-quinazolinone, monohydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
An antagonist of GHS-R1a (Ki = 0.017 µM); selective for GHS-R1a over the motilin receptor (Ki = 6 µM) and a panel of 30 receptors and enzymes (Kis = >10 µM); prevents ghrelin-induced decreases in insulin secretion in glucose-stimulated isolated rat pancreatic islets at 1 µM; increases plasma insulin levels and decreases blood glucose levels in rats in an intraperitoneal glucose tolerance test at 0.3 or 10 mg/kg, respectively; inhibits cocaine-induced hyperlocomotion in mice at 10 and 20 mg/kg
Storage Temperature:
-20°C