TFC 007
Catalogue number:
CAY17971-10 mg
Supplier:
Size:
10 mg
Product is available in:
£231.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
927878-49-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
487.6
Alternative Names:
n-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An H-PGDS inhibitor (IC50 = 0.083 µM); selective for H-PGDS over L-PGDS and mPGES at 100 µM; selective for H-PGDS over COX-1, COX-2, 5-LO, LTC4 synthase, and TX synthase, as well as the histamine H1 and CysLT1 receptors, at 10 µM; inhibits antigen-induced increases in the production of PGD2 in nasal cavity lavage fluid and reduces nasal blockage in a guinea pig model of allergic rhinitis at 30 mg/kg
Storage Temperature:
-20°C